BDBM50281096 CHEMBL86676::N-{(2E)-3-[3-(4-fluorophenoxy)phenyl]-1-methylprop-2-enyl}-N-hydroxyurea

SMILES: CC(\C=C\c1cccc(Oc2ccc(F)cc2)c1)N(O)C(N)=O

InChI Key: InChIKey=UAIYNMRLUHHRMF-AATRIKPKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50281096   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50281096 (CHEMBL86676 | N-{(2E)-3-[3-(4-fluorophenoxy)phenyl...) Show SMILES CC(\C=C\c1cccc(Oc2ccc(F)cc2)c1)N(O)C(N)=O Show InChI InChI=1S/C17H17FN2O3/c1-12(20(22)17(19)21)5-6-13-3-2-4-16(11-13)23-15-9-7-14(18)8-10-15/h2-12,22H,1H3,(H2,19,21)/b6-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was tested in vitro for inhibition against 5-lipoxygenase in intact human neutrophils				Bioorg Med Chem Lett 3: 2565-2570 (1993) Article DOI: 10.1016/S0960-894X(01)80717-4 BindingDB Entry DOI: 10.7270/Q2833RZX
					More data for this Ligand-Target Pair