BDBM50281480 CHEMBL87473::[1-Benzyl-3-(2,2-dimethyl-propylcarbamoyl)-3,3-difluoro-2-oxo-propyl]-carbamic acid benzyl ester

SMILES: CC(C)(C)CNC(=O)C(F)(F)C(=O)C(Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key: InChIKey=PGKUTYZXZWIMFV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50281480   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50281480 (CHEMBL87473 | [1-Benzyl-3-(2,2-dimethyl-propylcarb...) Show SMILES CC(C)(C)CNC(=O)C(F)(F)C(=O)C(Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C24H28F2N2O4/c1-23(2,3)16-27-21(30)24(25,26)20(29)19(14-17-10-6-4-7-11-17)28-22(31)32-15-18-12-8-5-9-13-18/h4-13,19H,14-16H2,1-3H3,(H,27,30)(H,28,31)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for inhibitory activity against the recombinant HIV-1 protease				Bioorg Med Chem Lett 3: 253-258 (1993) Article DOI: 10.1016/S0960-894X(01)80887-8 BindingDB Entry DOI: 10.7270/Q2RX9C0Q
					More data for this Ligand-Target Pair