BDBM50281719 CHEMBL169931::{3-[3-(3-Methoxy-phenyl)-ureido]-2-oxo-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-acetic acid

SMILES: COc1cccc(NC(=O)NC2CCc3ccccc3N(CC(O)=O)C2=O)c1

InChI Key: InChIKey=LDKASJPGQAISEW-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50281719 (CHEMBL169931 | {3-[3-(3-Methoxy-phenyl)-ureido]-2-...) Show SMILES COc1cccc(NC(=O)NC2CCc3ccccc3N(CC(O)=O)C2=O)c1 Show InChI InChI=1S/C20H21N3O5/c1-28-15-7-4-6-14(11-15)21-20(27)22-16-10-9-13-5-2-3-8-17(13)23(19(16)26)12-18(24)25/h2-8,11,16H,9-10,12H2,1H3,(H,24,25)(H2,21,22,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig cortex.				Bioorg Med Chem Lett 3: 871-874 (1993) Article DOI: 10.1016/S0960-894X(00)80683-6 BindingDB Entry DOI: 10.7270/Q2513Z41
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50281719 (CHEMBL169931 | {3-[3-(3-Methoxy-phenyl)-ureido]-2-...) Show SMILES COc1cccc(NC(=O)NC2CCc3ccccc3N(CC(O)=O)C2=O)c1 Show InChI InChI=1S/C20H21N3O5/c1-28-15-7-4-6-14(11-15)21-20(27)22-16-10-9-13-5-2-3-8-17(13)23(19(16)26)12-18(24)25/h2-8,11,16H,9-10,12H2,1H3,(H,24,25)(H2,21,22,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [125I]-gastrin to gastric glands in guinea pig.				Bioorg Med Chem Lett 3: 871-874 (1993) Article DOI: 10.1016/S0960-894X(00)80683-6 BindingDB Entry DOI: 10.7270/Q2513Z41
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50281719 (CHEMBL169931 | {3-[3-(3-Methoxy-phenyl)-ureido]-2-...) Show SMILES COc1cccc(NC(=O)NC2CCc3ccccc3N(CC(O)=O)C2=O)c1 Show InChI InChI=1S/C20H21N3O5/c1-28-15-7-4-6-14(11-15)21-20(27)22-16-10-9-13-5-2-3-8-17(13)23(19(16)26)12-18(24)25/h2-8,11,16H,9-10,12H2,1H3,(H,24,25)(H2,21,22,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreas.				Bioorg Med Chem Lett 3: 871-874 (1993) Article DOI: 10.1016/S0960-894X(00)80683-6 BindingDB Entry DOI: 10.7270/Q2513Z41
					More data for this Ligand-Target Pair