BDBM50281725 CHEMBL355319::[3-(3-Naphthalen-1-yl-ureido)-2-oxo-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl]-acetic acid tert-butyl ester

SMILES: CC(C)(C)OC(=O)CN1c2ccccc2CCC(NC(=O)Nc2cccc3ccccc23)C1=O

InChI Key: InChIKey=ASWMJVZBNJCXGG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (RAT)	BDBM50281725 (CHEMBL355319 | [3-(3-Naphthalen-1-yl-ureido)-2-oxo...) Show SMILES CC(C)(C)OC(=O)CN1c2ccccc2CCC(NC(=O)Nc2cccc3ccccc23)C1=O Show InChI InChI=1S/C27H29N3O4/c1-27(2,3)34-24(31)17-30-23-14-7-5-10-19(23)15-16-22(25(30)32)29-26(33)28-21-13-8-11-18-9-4-6-12-20(18)21/h4-14,22H,15-17H2,1-3H3,(H2,28,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreas.				Bioorg Med Chem Lett 3: 871-874 (1993) Article DOI: 10.1016/S0960-894X(00)80683-6 BindingDB Entry DOI: 10.7270/Q2513Z41
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50281725 (CHEMBL355319 | [3-(3-Naphthalen-1-yl-ureido)-2-oxo...) Show SMILES CC(C)(C)OC(=O)CN1c2ccccc2CCC(NC(=O)Nc2cccc3ccccc23)C1=O Show InChI InChI=1S/C27H29N3O4/c1-27(2,3)34-24(31)17-30-23-14-7-5-10-19(23)15-16-22(25(30)32)29-26(33)28-21-13-8-11-18-9-4-6-12-20(18)21/h4-14,22H,15-17H2,1-3H3,(H2,28,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig cortex.				Bioorg Med Chem Lett 3: 871-874 (1993) Article DOI: 10.1016/S0960-894X(00)80683-6 BindingDB Entry DOI: 10.7270/Q2513Z41
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50281725 (CHEMBL355319 | [3-(3-Naphthalen-1-yl-ureido)-2-oxo...) Show SMILES CC(C)(C)OC(=O)CN1c2ccccc2CCC(NC(=O)Nc2cccc3ccccc23)C1=O Show InChI InChI=1S/C27H29N3O4/c1-27(2,3)34-24(31)17-30-23-14-7-5-10-19(23)15-16-22(25(30)32)29-26(33)28-21-13-8-11-18-9-4-6-12-20(18)21/h4-14,22H,15-17H2,1-3H3,(H2,28,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [125I]-gastrin to gastric glands in guinea pig.				Bioorg Med Chem Lett 3: 871-874 (1993) Article DOI: 10.1016/S0960-894X(00)80683-6 BindingDB Entry DOI: 10.7270/Q2513Z41
					More data for this Ligand-Target Pair