BDBM50281728 CHEMBL170068::[3-(3-Naphthalen-1-yl-ureido)-2-oxo-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl]-acetic acid

SMILES: OC(=O)CN1c2ccccc2CCC(NC(=O)Nc2cccc3ccccc23)C1=O

InChI Key: InChIKey=YNPNGAFWYCZGIR-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281728   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50281728 (CHEMBL170068 | [3-(3-Naphthalen-1-yl-ureido)-2-oxo...) Show SMILES OC(=O)CN1c2ccccc2CCC(NC(=O)Nc2cccc3ccccc23)C1=O Show InChI InChI=1S/C23H21N3O4/c27-21(28)14-26-20-11-4-2-7-16(20)12-13-19(22(26)29)25-23(30)24-18-10-5-8-15-6-1-3-9-17(15)18/h1-11,19H,12-14H2,(H,27,28)(H2,24,25,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig cortex.				Bioorg Med Chem Lett 3: 871-874 (1993) Article DOI: 10.1016/S0960-894X(00)80683-6 BindingDB Entry DOI: 10.7270/Q2513Z41
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50281728 (CHEMBL170068 | [3-(3-Naphthalen-1-yl-ureido)-2-oxo...) Show SMILES OC(=O)CN1c2ccccc2CCC(NC(=O)Nc2cccc3ccccc23)C1=O Show InChI InChI=1S/C23H21N3O4/c27-21(28)14-26-20-11-4-2-7-16(20)12-13-19(22(26)29)25-23(30)24-18-10-5-8-15-6-1-3-9-17(15)18/h1-11,19H,12-14H2,(H,27,28)(H2,24,25,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig cortex.				Bioorg Med Chem Lett 3: 871-874 (1993) Article DOI: 10.1016/S0960-894X(00)80683-6 BindingDB Entry DOI: 10.7270/Q2513Z41
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50281728 (CHEMBL170068 | [3-(3-Naphthalen-1-yl-ureido)-2-oxo...) Show SMILES OC(=O)CN1c2ccccc2CCC(NC(=O)Nc2cccc3ccccc23)C1=O Show InChI InChI=1S/C23H21N3O4/c27-21(28)14-26-20-11-4-2-7-16(20)12-13-19(22(26)29)25-23(30)24-18-10-5-8-15-6-1-3-9-17(15)18/h1-11,19H,12-14H2,(H,27,28)(H2,24,25,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreas.				Bioorg Med Chem Lett 3: 871-874 (1993) Article DOI: 10.1016/S0960-894X(00)80683-6 BindingDB Entry DOI: 10.7270/Q2513Z41
					More data for this Ligand-Target Pair