BDBM50282067 1-((2R,4S,5S)-4-Hydroxy-5-methoxy-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione::CHEMBL289441

SMILES: CO[C@H]1O[C@H](C[C@@H]1O)n1cc(C)c(=O)[nH]c1=O

InChI Key: InChIKey=IXDUVZSLQPFQQK-OOZYFLPDSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidine kinase, cytosolic (Homo sapiens (Human))	BDBM50282067 (1-((2R,4S,5S)-4-Hydroxy-5-methoxy-tetrahydro-furan...) Show SMILES CO[C@H]1O[C@H](C[C@@H]1O)n1cc(C)c(=O)[nH]c1=O Show InChI InChI=1S/C10H14N2O5/c1-5-4-12(10(15)11-8(5)14)7-3-6(13)9(16-2)17-7/h4,6-7,9,13H,3H2,1-2H3,(H,11,14,15)/t6-,7+,9-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound against HSV-1 Thymidine kinase				Bioorg Med Chem Lett 3: 1571-1576 (1993) Article DOI: 10.1016/S0960-894X(00)80020-7 BindingDB Entry DOI: 10.7270/Q28P60F3
					More data for this Ligand-Target Pair
Thymidine kinase, cytosolic (Homo sapiens (Human))	BDBM50282067 (1-((2R,4S,5S)-4-Hydroxy-5-methoxy-tetrahydro-furan...) Show SMILES CO[C@H]1O[C@H](C[C@@H]1O)n1cc(C)c(=O)[nH]c1=O Show InChI InChI=1S/C10H14N2O5/c1-5-4-12(10(15)11-8(5)14)7-3-6(13)9(16-2)17-7/h4,6-7,9,13H,3H2,1-2H3,(H,11,14,15)/t6-,7+,9-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HSV-1 Thymidine kinase				Bioorg Med Chem Lett 3: 1571-1576 (1993) Article DOI: 10.1016/S0960-894X(00)80020-7 BindingDB Entry DOI: 10.7270/Q28P60F3
					More data for this Ligand-Target Pair