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BDBM50282136 6-Isopropyl-3-(5-phenylsulfamoyl-pentyl)-azulene-1-carboxylic acid::CHEMBL297275

SMILES: CC(C)c1ccc2c(CCCCCS(=O)(=O)Nc3ccccc3)cc(C(O)=O)c2cc1

InChI Key: InChIKey=WOHOGBVYNVOMOQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282136   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thromboxane A2 receptor


(RAT)		BDBM50282136
PNG
(6-Isopropyl-3-(5-phenylsulfamoyl-pentyl)-azulene-1...)
Show SMILES CC(C)c1ccc2c(CCCCCS(=O)(=O)Nc3ccccc3)cc(C(O)=O)c2cc1
Show InChI InChI=1S/C25H29NO4S/c1-18(2)19-12-14-22-20(17-24(25(27)28)23(22)15-13-19)9-5-4-8-16-31(29,30)26-21-10-6-3-7-11-21/h3,6-7,10-15,17-18,26H,4-5,8-9,16H2,1-2H3,(H,27,28)
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Similars
Article
n/an/a 1.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)

Bioorg Med Chem Lett 3: 1687-1692 (1993)


Article DOI: 10.1016/S0960-894X(00)80043-8
BindingDB Entry DOI: 10.7270/Q2H70FQG
More data for this
Ligand-Target Pair