BDBM50282273 CHEMBL67921::Imidazo[4,5-b]pyridine derivative

SMILES: CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc3c(C)c(NC(=O)CCC)cnc23)cc1

InChI Key: InChIKey=HQFMXUUQMSPIBV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282273   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50282273 (CHEMBL67921 | Imidazo[4,5-b]pyridine derivative) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc3c(C)c(NC(=O)CCC)cnc23)cc1 Show InChI InChI=1S/C32H39N5O5S/c1-5-8-19-42-32(39)36-43(40,41)27-14-10-9-13-25(27)24-17-15-23(16-18-24)21-37-28(11-6-2)35-30-22(4)26(20-33-31(30)37)34-29(38)12-7-3/h9-10,13-18,20H,5-8,11-12,19,21H2,1-4H3,(H,34,38)(H,36,39)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.510	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type ...				Bioorg Med Chem Lett 4: 17-22 (1994) Article DOI: 10.1016/S0960-894X(01)81115-X BindingDB Entry DOI: 10.7270/Q2G73DPF
					More data for this Ligand-Target Pair
Angiotensin II AT2 (RAT)	BDBM50282273 (CHEMBL67921 | Imidazo[4,5-b]pyridine derivative) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc3c(C)c(NC(=O)CCC)cnc23)cc1 Show InChI InChI=1S/C32H39N5O5S/c1-5-8-19-42-32(39)36-43(40,41)27-14-10-9-13-25(27)24-17-15-23(16-18-24)21-37-28(11-6-2)35-30-22(4)26(20-33-31(30)37)34-29(38)12-7-3/h9-10,13-18,20H,5-8,11-12,19,21H2,1-4H3,(H,34,38)(H,36,39)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from AT2 receptor in rat midbrain m...				Bioorg Med Chem Lett 4: 17-22 (1994) Article DOI: 10.1016/S0960-894X(01)81115-X BindingDB Entry DOI: 10.7270/Q2G73DPF
					More data for this Ligand-Target Pair