BDBM50282379 2-Propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1H-imidazo[1,2-b]pyrazole-7-carboxylic acid::CHEMBL128920

SMILES: CCCc1cn2ncc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=FKSQNLMGHVITGQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282379   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (Bos taurus)	BDBM50282379 (2-Propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...) Show SMILES CCCc1cn2ncc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C23H21N7O2/c1-2-5-17-14-30-22(20(12-24-30)23(31)32)29(17)13-15-8-10-16(11-9-15)18-6-3-4-7-19(18)21-25-27-28-26-21/h3-4,6-12,14H,2,5,13H2,1H3,(H,31,32)(H,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required to inhibit [125I]-AII binding to Angiotensin II receptor from membrane fractions of bovine adrenal cortex				Bioorg Med Chem Lett 4: 35-40 (1994) Article DOI: 10.1016/S0960-894X(01)81118-5 BindingDB Entry DOI: 10.7270/Q21Z44CP
					More data for this Ligand-Target Pair