BDBM50282469 CHEMBL352502::Quinazolinone Analog

SMILES: CCCc1nc2ccc(NC(=O)c3ccccc3)cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C

InChI Key: InChIKey=CIHDNNQJOZYLEP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282469   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT2 (RAT)	BDBM50282469 (CHEMBL352502 | Quinazolinone Analog) Show SMILES CCCc1nc2ccc(NC(=O)c3ccccc3)cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C37H38N4O6S/c1-4-10-34-39-32-20-19-29(38-35(42)28-11-6-5-7-12-28)23-31(32)36(43)41(34)24-26-15-17-27(18-16-26)30-13-8-9-14-33(30)48(45,46)40-37(44)47-22-21-25(2)3/h5-9,11-20,23,25H,4,10,21-22,24H2,1-3H3,(H,38,42)(H,40,44)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro for binding affinity against angiotensin II receptor type 2 in rat midbrain membrane				Bioorg Med Chem Lett 4: 81-86 (1994) Article DOI: 10.1016/S0960-894X(01)81126-4 BindingDB Entry DOI: 10.7270/Q2D79BBS
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50282469 (CHEMBL352502 | Quinazolinone Analog) Show SMILES CCCc1nc2ccc(NC(=O)c3ccccc3)cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C37H38N4O6S/c1-4-10-34-39-32-20-19-29(38-35(42)28-11-6-5-7-12-28)23-31(32)36(43)41(34)24-26-15-17-27(18-16-26)30-13-8-9-14-33(30)48(45,46)40-37(44)47-22-21-25(2)3/h5-9,11-20,23,25H,4,10,21-22,24H2,1-3H3,(H,38,42)(H,40,44)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membrane				Bioorg Med Chem Lett 4: 81-86 (1994) Article DOI: 10.1016/S0960-894X(01)81126-4 BindingDB Entry DOI: 10.7270/Q2D79BBS
					More data for this Ligand-Target Pair