BDBM50282582 (4S,6S)-4,6-Dibenzyl-5-hydroxy-tetrahydro-pyrimidin-2-one::CHEMBL25704

SMILES: OC1[C@H](Cc2ccccc2)NC(=O)N[C@H]1Cc1ccccc1

InChI Key: InChIKey=CMNDRGWYZFNWCC-HOTGVXAUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 protease (Human immunodeficiency virus type 1)	BDBM50282582 ((4S,6S)-4,6-Dibenzyl-5-hydroxy-tetrahydro-pyrimidi...) Show SMILES OC1[C@H](Cc2ccccc2)NC(=O)N[C@H]1Cc1ccccc1 Show InChI InChI=1S/C18H20N2O2/c21-17-15(11-13-7-3-1-4-8-13)19-18(22)20-16(17)12-14-9-5-2-6-10-14/h1-10,15-17,21H,11-12H2,(H2,19,20,22)/t15-,16-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound was determined against HIV-1 protease				Bioorg Med Chem Lett 4: 1247-1252 (1994) Article DOI: 10.1016/S0960-894X(01)80339-5 BindingDB Entry DOI: 10.7270/Q2MS3SQ6
					More data for this Ligand-Target Pair