BDBM50282864 2-(4-Methyl-4H-[1,2,4]triazol-3-ylsulfanylmethyl)-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one::CHEMBL50526

SMILES: Cn1cnnc1SCN1C(=O)c2ccccc2S1(=O)=O

InChI Key: InChIKey=OJJCDCHQZPCTHN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282864   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50282864 (2-(4-Methyl-4H-[1,2,4]triazol-3-ylsulfanylmethyl)-...) Show SMILES Cn1cnnc1SCN1C(=O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C11H10N4O3S2/c1-14-6-12-13-11(14)19-7-15-10(16)8-4-2-3-5-9(8)20(15,17)18/h2-6H,7H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	246	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Potency of Inhibition of human leukocyte elastase (HLE) expressed as apparent binding constant				Bioorg Med Chem Lett 4: 1801-1806 (1994) Article DOI: 10.1016/S0960-894X(01)80374-7 BindingDB Entry DOI: 10.7270/Q25M65PP
					More data for this Ligand-Target Pair