BDBM50283049 (Z)-7-[(1R,2R,3S,5S)-5-(Biphenyl-4-ylmethoxy)-3-hydroxy-2-piperidin-1-yl-cyclopentyl]-hept-4-enoic acid::CHEMBL65030::GR 32191::GR-32191
SMILES: O[C@H]1C[C@H](OCc2ccc(cc2)-c2ccccc2)[C@H](CC\C=C/CCC(O)=O)[C@H]1N1CCCCC1
InChI Key: InChIKey=GQGRDYWMOPRROR-XUSMOFMBSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Prostanoid TP receptor (Homo sapiens (Human)) | BDBM50283049 ((Z)-7-[(1R,2R,3S,5S)-5-(Biphenyl-4-ylmethoxy)-3-hy...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by PDSP Ki Database | Psychopharmacology (Berl) 124: 57-73 (1996) Article DOI: 10.1007/bf02245606 BindingDB Entry DOI: 10.7270/Q2610XV6 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane Alpha (MOUSE) | BDBM50283049 ((Z)-7-[(1R,2R,3S,5S)-5-(Biphenyl-4-ylmethoxy)-3-hy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Curated by PDSP Ki Database | Br J Pharmacol 122: 217-24 (1997) Article DOI: 10.1038/sj.bjp.0701367 BindingDB Entry DOI: 10.7270/Q26M35CT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid TP receptor (Homo sapiens (Human)) | BDBM50283049 ((Z)-7-[(1R,2R,3S,5S)-5-(Biphenyl-4-ylmethoxy)-3-hy...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro thromboxane receptor antagonist activity was determined by inhibition of U-46619 induced aggregation of washed human platelets | Bioorg Med Chem Lett 4: 2067-2072 (1994) Article DOI: 10.1016/S0960-894X(01)80103-7 BindingDB Entry DOI: 10.7270/Q2GX4BG6 | |||||||||||
More data for this Ligand-Target Pair |