BDBM50283336 4-{2-[3-(4-Fluoro-phenyl)-prop-2-ynyloxy]-ethyl}-1-phenethyl-piperidine::CHEMBL308098

SMILES: Fc1ccc(cc1)C#CCOCCC1CCN(CCc2ccccc2)CC1

InChI Key: InChIKey=URDHIIFLGMSALF-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50283336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283336 (4-{2-[3-(4-Fluoro-phenyl)-prop-2-ynyloxy]-ethyl}-1...) Show SMILES Fc1ccc(cc1)C#CCOCCC1CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C24H28FNO/c25-24-10-8-22(9-11-24)7-4-19-27-20-15-23-13-17-26(18-14-23)16-12-21-5-2-1-3-6-21/h1-3,5-6,8-11,23H,12-20H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards sigma receptor using [3H]-(+)-SKF-10,047 as radioligand				Bioorg Med Chem Lett 4: 2347-2352 (1994) Article DOI: 10.1016/0960-894X(94)85038-0 BindingDB Entry DOI: 10.7270/Q2S75G8F
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Homo sapiens (Human))	BDBM50283336 (4-{2-[3-(4-Fluoro-phenyl)-prop-2-ynyloxy]-ethyl}-1...) Show SMILES Fc1ccc(cc1)C#CCOCCC1CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C24H28FNO/c25-24-10-8-22(9-11-24)7-4-19-27-20-15-23-13-17-26(18-14-23)16-12-21-5-2-1-3-6-21/h1-3,5-6,8-11,23H,12-20H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligand				Bioorg Med Chem Lett 4: 2347-2352 (1994) Article DOI: 10.1016/0960-894X(94)85038-0 BindingDB Entry DOI: 10.7270/Q2S75G8F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50283336 (4-{2-[3-(4-Fluoro-phenyl)-prop-2-ynyloxy]-ethyl}-1...) Show SMILES Fc1ccc(cc1)C#CCOCCC1CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C24H28FNO/c25-24-10-8-22(9-11-24)7-4-19-27-20-15-23-13-17-26(18-14-23)16-12-21-5-2-1-3-6-21/h1-3,5-6,8-11,23H,12-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards Dopamine receptor D2 using [3H]-spiperone as radioligand				Bioorg Med Chem Lett 4: 2347-2352 (1994) Article DOI: 10.1016/0960-894X(94)85038-0 BindingDB Entry DOI: 10.7270/Q2S75G8F
					More data for this Ligand-Target Pair