BDBM50283469 2-Phenylamino-5H-[1,3]thiazino[5,4-b]indol-4-one::CHEMBL78475

SMILES: Oc1sc(Nc2ccccc2)nc2c3ccccc3nc12

InChI Key: InChIKey=WXEHSNPNEFNBDV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50283469   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50283469 (2-Phenylamino-5H-[1,3]thiazino[5,4-b]indol-4-one |...) Show SMILES Oc1sc(Nc2ccccc2)nc2c3ccccc3nc12 Show InChI InChI=1S/C16H11N3OS/c20-15-14-13(11-8-4-5-9-12(11)18-14)19-16(21-15)17-10-6-2-1-3-7-10/h1-9,20H,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for inhibition of human leukocyte Elastase at 64 microM concentration from human polymorphonuclear leukocytes				Bioorg Med Chem Lett 4: 2399-2404 (1994) Article DOI: 10.1016/S0960-894X(01)80398-X BindingDB Entry DOI: 10.7270/Q2BZ65Z8
					More data for this Ligand-Target Pair