BDBM50283632 (S)-3-Biphenyl-4-yl-2-[(S)-2-(phosphonomethyl-amino)-3-thiophen-2-yl-propionylamino]-propionic acid::CHEMBL330507

SMILES: OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1cccs1)NCP(O)(O)=O

InChI Key: InChIKey=ITMQFUGUIZVZNR-SFTDATJTSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283632   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ACEI-ACE2 (Homo sapiens (Human))	BDBM50283632 ((S)-3-Biphenyl-4-yl-2-[(S)-2-(phosphonomethyl-amin...) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1cccs1)NCP(O)(O)=O Show InChI InChI=1S/C23H25N2O6PS/c26-22(20(24-15-32(29,30)31)14-19-7-4-12-33-19)25-21(23(27)28)13-16-8-10-18(11-9-16)17-5-2-1-3-6-17/h1-12,20-21,24H,13-15H2,(H,25,26)(H,27,28)(H2,29,30,31)/t20-,21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	385	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against angiotensin-converting enzyme				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50283632 ((S)-3-Biphenyl-4-yl-2-[(S)-2-(phosphonomethyl-amin...) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1cccs1)NCP(O)(O)=O Show InChI InChI=1S/C23H25N2O6PS/c26-22(20(24-15-32(29,30)31)14-19-7-4-12-33-19)25-21(23(27)28)13-16-8-10-18(11-9-16)17-5-2-1-3-6-17/h1-12,20-21,24H,13-15H2,(H,25,26)(H,27,28)(H2,29,30,31)/t20-,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against neutral endopeptidase				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair