BDBM50283637 2-{(S)-3-Biphenyl-4-yl-2-[(S)-3-methyl-1-oxo-2-(phosphonomethyl-amino)-butylamino]-propionylamino}-3-((S)-4-hydroxy-phenyl)-propionic acid::CHEMBL329894

SMILES: CC(C)[C@H](NCP(O)(O)=O)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI Key: InChIKey=MEAOSULJCSUBOP-QKDODKLFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283637   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ACEI-ACE2 (Homo sapiens (Human))	BDBM50283637 (2-{(S)-3-Biphenyl-4-yl-2-[(S)-3-methyl-1-oxo-2-(ph...) Show SMILES CC(C)[C@H](NCP(O)(O)=O)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C30H36N3O8P/c1-19(2)27(31-18-42(39,40)41)29(36)32-25(16-20-8-12-23(13-9-20)22-6-4-3-5-7-22)28(35)33-26(30(37)38)17-21-10-14-24(34)15-11-21/h3-15,19,25-27,31,34H,16-18H2,1-2H3,(H,32,36)(H,33,35)(H,37,38)(H2,39,40,41)/t25-,26-,27-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against angiotensin-converting enzyme				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50283637 (2-{(S)-3-Biphenyl-4-yl-2-[(S)-3-methyl-1-oxo-2-(ph...) Show SMILES CC(C)[C@H](NCP(O)(O)=O)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C30H36N3O8P/c1-19(2)27(31-18-42(39,40)41)29(36)32-25(16-20-8-12-23(13-9-20)22-6-4-3-5-7-22)28(35)33-26(30(37)38)17-21-10-14-24(34)15-11-21/h3-15,19,25-27,31,34H,16-18H2,1-2H3,(H,32,36)(H,33,35)(H,37,38)(H2,39,40,41)/t25-,26-,27-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against neutral endopeptidase				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair