BDBM50283652 (S)-3-Biphenyl-4-yl-2-[(S)-3-phenyl-2-(phosphonomethyl-amino)-propionylamino]-propionic acid::CHEMBL93180

SMILES: OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1ccccc1)NCP(O)(O)=O

InChI Key: InChIKey=ZMFXEDLVSXEQSM-GOTSBHOMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283652   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ACEI-ACE2 (Homo sapiens (Human))	BDBM50283652 ((S)-3-Biphenyl-4-yl-2-[(S)-3-phenyl-2-(phosphonome...) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1ccccc1)NCP(O)(O)=O Show InChI InChI=1S/C25H27N2O6P/c28-24(22(26-17-34(31,32)33)15-18-7-3-1-4-8-18)27-23(25(29)30)16-19-11-13-21(14-12-19)20-9-5-2-6-10-20/h1-14,22-23,26H,15-17H2,(H,27,28)(H,29,30)(H2,31,32,33)/t22-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against angiotensin-converting enzyme				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50283652 ((S)-3-Biphenyl-4-yl-2-[(S)-3-phenyl-2-(phosphonome...) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1ccccc1)NCP(O)(O)=O Show InChI InChI=1S/C25H27N2O6P/c28-24(22(26-17-34(31,32)33)15-18-7-3-1-4-8-18)27-23(25(29)30)16-19-11-13-21(14-12-19)20-9-5-2-6-10-20/h1-14,22-23,26H,15-17H2,(H,27,28)(H,29,30)(H2,31,32,33)/t22-,23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against neutral endopeptidase				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair