BDBM50283657 (S)-3-Biphenyl-4-yl-2-[(S)-2-cyclohexyl-2-(phosphonomethyl-amino)-acetylamino]-propionic acid::CHEMBL92638

SMILES: OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@@H](NCP(O)(O)=O)C1CCCCC1

InChI Key: InChIKey=PLBVLVOORHYKJM-VXKWHMMOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ACEI-ACE2 (Homo sapiens (Human))	BDBM50283657 ((S)-3-Biphenyl-4-yl-2-[(S)-2-cyclohexyl-2-(phospho...) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@@H](NCP(O)(O)=O)C1CCCCC1 Show InChI InChI=1S/C24H31N2O6P/c27-23(22(25-16-33(30,31)32)20-9-5-2-6-10-20)26-21(24(28)29)15-17-11-13-19(14-12-17)18-7-3-1-4-8-18/h1,3-4,7-8,11-14,20-22,25H,2,5-6,9-10,15-16H2,(H,26,27)(H,28,29)(H2,30,31,32)/t21-,22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against angiotensin-converting enzyme				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50283657 ((S)-3-Biphenyl-4-yl-2-[(S)-2-cyclohexyl-2-(phospho...) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@@H](NCP(O)(O)=O)C1CCCCC1 Show InChI InChI=1S/C24H31N2O6P/c27-23(22(25-16-33(30,31)32)20-9-5-2-6-10-20)26-21(24(28)29)15-17-11-13-19(14-12-17)18-7-3-1-4-8-18/h1,3-4,7-8,11-14,20-22,25H,2,5-6,9-10,15-16H2,(H,26,27)(H,28,29)(H2,30,31,32)/t21-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration against neutral endopeptidase				Bioorg Med Chem Lett 4: 2715-2720 (1994) Article DOI: 10.1016/S0960-894X(01)80703-4 BindingDB Entry DOI: 10.7270/Q2SB467B
					More data for this Ligand-Target Pair