BDBM50283735 (S)-2-{(R)-2-[3-((R)-2-Amino-3-mercapto-propionylamino)-phenyl]-3-phenyl-propionylamino}-4-methylsulfanyl-butyric acid::CHEMBL96295

SMILES: CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)c1cccc(NC(=O)[C@@H](N)CS)c1)C(O)=O

InChI Key: InChIKey=QMIBTVLDZQQTIC-AABGKKOBSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283735   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50283735 ((S)-2-{(R)-2-[3-((R)-2-Amino-3-mercapto-propionyla...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)c1cccc(NC(=O)[C@@H](N)CS)c1)C(O)=O Show InChI InChI=1S/C23H29N3O4S2/c1-32-11-10-20(23(29)30)26-21(27)18(12-15-6-3-2-4-7-15)16-8-5-9-17(13-16)25-22(28)19(24)14-31/h2-9,13,18-20,31H,10-12,14,24H2,1H3,(H,25,28)(H,26,27)(H,29,30)/t18-,19+,20+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against geranylgeranyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50283735 ((S)-2-{(R)-2-[3-((R)-2-Amino-3-mercapto-propionyla...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)c1cccc(NC(=O)[C@@H](N)CS)c1)C(O)=O Show InChI InChI=1S/C23H29N3O4S2/c1-32-11-10-20(23(29)30)26-21(27)18(12-15-6-3-2-4-7-15)16-8-5-9-17(13-16)25-22(28)19(24)14-31/h2-9,13,18-20,31H,10-12,14,24H2,1H3,(H,25,28)(H,26,27)(H,29,30)/t18-,19+,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair