BDBM50283882 3-methoxy-4-[4-methoxyphenyl(methyl)carboxamido]-2-methyl-16-oxo-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaene::CHEMBL132169

SMILES: CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccc(OC)cc1

InChI Key: InChIKey=IXOVKVHWGKDXKQ-HRWXUNOHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50283882   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50283882 (3-methoxy-4-[4-methoxyphenyl(methyl)carboxamido]-2...) Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C36H32N4O5/c1-36-33(44-4)26(38(2)35(42)19-13-15-20(43-3)16-14-19)17-27(45-36)39-24-11-7-5-9-21(24)29-30-23(18-37-34(30)41)28-22-10-6-8-12-25(22)40(36)32(28)31(29)39/h5-16,26-27,33H,17-18H2,1-4H3,(H,37,41)/t26-,27-,33-,36+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined				Bioorg Med Chem Lett 4: 399-404 (1994) Article DOI: 10.1016/0960-894X(94)80004-9 BindingDB Entry DOI: 10.7270/Q2R211BD
					More data for this Ligand-Target Pair