BDBM50283900 4-ethyl(methyl)amino-3-methoxy-2-methyl-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::CHEMBL129946

SMILES: CCN(C)[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13

InChI Key: InChIKey=YUAWUNMKPARPJD-VZYCLNPTSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283900   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50283900 (4-ethyl(methyl)amino-3-methoxy-2-methyl-(2R,3S,4S,...) Show SMILES CCN(C)[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C30H30N4O3/c1-5-32(3)21-14-22-33-19-12-8-6-10-16(19)24-25-18(15-31-29(25)35)23-17-11-7-9-13-20(17)34(27(23)26(24)33)30(2,37-22)28(21)36-4/h6-13,21-22,28H,5,14-15H2,1-4H3,(H,31,35)/t21-,22-,28-,30+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined				Bioorg Med Chem Lett 4: 399-404 (1994) Article DOI: 10.1016/0960-894X(94)80004-9 BindingDB Entry DOI: 10.7270/Q2R211BD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50283900 (4-ethyl(methyl)amino-3-methoxy-2-methyl-(2R,3S,4S,...) Show SMILES CCN(C)[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C30H30N4O3/c1-5-32(3)21-14-22-33-19-12-8-6-10-16(19)24-25-18(15-31-29(25)35)23-17-11-7-9-13-20(17)34(27(23)26(24)33)30(2,37-22)28(21)36-4/h6-13,21-22,28H,5,14-15H2,1-4H3,(H,31,35)/t21-,22-,28-,30+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Src tyrosine kinase				Bioorg Med Chem Lett 4: 399-404 (1994) Article DOI: 10.1016/0960-894X(94)80004-9 BindingDB Entry DOI: 10.7270/Q2R211BD
					More data for this Ligand-Target Pair