BDBM50283917 1-(1,1-Diphenyl-silolan-3-yl)-4-(4-fluoro-phenyl)-piperazine::CHEMBL337226

SMILES: Fc1ccc(cc1)N1CCN(CC1)C1CC[Si](C1)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=SSIMRFYYUFVKNG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50283917   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50283917 (1-(1,1-Diphenyl-silolan-3-yl)-4-(4-fluoro-phenyl)-...) Show SMILES Fc1ccc(cc1)N1CCN(CC1)C1CC[Si](C1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H29FN2Si/c27-22-11-13-23(14-12-22)28-16-18-29(19-17-28)24-15-20-30(21-24,25-7-3-1-4-8-25)26-9-5-2-6-10-26/h1-14,24H,15-21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligand				Bioorg Med Chem Lett 4: 415-420 (1994) Article DOI: 10.1016/0960-894X(94)80007-3 BindingDB Entry DOI: 10.7270/Q2HX1D6M
					More data for this Ligand-Target Pair