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SMILES: OC(=O)CCNC(=O)C(Cc1ccc(cc1)-c1ccccc1)S(=O)(=O)CP(O)(O)=O

InChI Key: InChIKey=KSMRYGYJCPJIEJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50283967   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Rattus norvegicus (Rat))		BDBM50283967
PNG
(3-(3-Biphenyl-4-yl-2-phosphonomethanesulfonyl-prop...)
Show SMILES OC(=O)CCNC(=O)C(Cc1ccc(cc1)-c1ccccc1)S(=O)(=O)CP(O)(O)=O
Show InChI InChI=1S/C19H22NO8PS/c21-18(22)10-11-20-19(23)17(30(27,28)13-29(24,25)26)12-14-6-8-16(9-7-14)15-4-2-1-3-5-15/h1-9,17H,10-13H2,(H,20,23)(H,21,22)(H2,24,25,26)
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Similars
Article
n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against neutral endopeptidase (NEP 24.11) from rat kidney cortex membranes

Bioorg Med Chem Lett 4: 539-542 (1994)


Article DOI: 10.1016/S0960-894X(01)80150-5
BindingDB Entry DOI: 10.7270/Q2736QV0
More data for this
Ligand-Target Pair