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BDBM50284056 CHEMBL4160327

SMILES: Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cc(O)ccc1O)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cc(O)ccc1O

InChI Key: InChIKey=HLPRNUOZUUZAOM-DMMXZFMDSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284056   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))
BDBM50284056
PNG
(CHEMBL4160327)
Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cc(O)ccc1O)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cc(O)ccc1O
Show InChI InChI=1S/C40H32N6O6/c1-22-2-4-23(5-3-22)38(32-20-41-34-10-6-24(16-30(32)34)39(51)45-43-18-26-14-28(47)8-12-36(26)49)33-21-42-35-11-7-25(17-31(33)35)40(52)46-44-19-27-15-29(48)9-13-37(27)50/h2-21,38,41-42,47-50H,1H3,(H,45,51)(H,46,52)/b43-18+,44-19+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.14E+3n/an/an/an/an/an/a



Imam Abdulrahman Bin Faisal University

Curated by ChEMBL


Assay Description
Inhibition of human beta-glucuronidase


Eur J Med Chem 143: 1757-1767 (2018)


Article DOI: 10.1016/j.ejmech.2017.10.071
BindingDB Entry DOI: 10.7270/Q23N25X1
More data for this
Ligand-Target Pair