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BDBM50284063 CHEMBL4164077

SMILES: Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(Cl)cc1)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(Cl)cc1

InChI Key: InChIKey=FPNBRYSBKUXVQY-FTNJMUCTSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284063   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
beta-Glucuronidase (β-glucuronidase)


(Homo sapiens (Human))		BDBM50284063
PNG
(CHEMBL4164077)
Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(Cl)cc1)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(Cl)cc1
Show InChI InChI=1S/C40H30Cl2N6O2/c1-24-2-8-27(9-3-24)38(34-22-43-36-16-10-28(18-32(34)36)39(49)47-45-20-25-4-12-30(41)13-5-25)35-23-44-37-17-11-29(19-33(35)37)40(50)48-46-21-26-6-14-31(42)15-7-26/h2-23,38,43-44H,1H3,(H,47,49)(H,48,50)/b45-20+,46-21+
PDB

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PC cid
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UniChem

Similars
Article
PubMed
n/an/a 5.80E+3n/an/an/an/an/an/a



Imam Abdulrahman Bin Faisal University

Curated by ChEMBL


Assay Description
Inhibition of human beta-glucuronidase

Eur J Med Chem 143: 1757-1767 (2018)


Article DOI: 10.1016/j.ejmech.2017.10.071
BindingDB Entry DOI: 10.7270/Q23N25X1
More data for this
Ligand-Target Pair