BDBM50284075 CHEMBL4171988

SMILES: Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\C=C\c1ccccc1)c1c[nH]c2ccc(cc12)C(=O)N\N=C\C=C\c1ccccc1

InChI Key: InChIKey=OLDYOFSQNJUTPH-IACXJJIDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284075   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
beta-Glucuronidase (β-glucuronidase) (Homo sapiens (Human))	BDBM50284075 (CHEMBL4171988) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\C=C\c1ccccc1)c1c[nH]c2ccc(cc12)C(=O)N\N=C\C=C\c1ccccc1 Show InChI InChI=1S/C44H36N6O2/c1-30-16-18-33(19-17-30)42(38-28-45-40-22-20-34(26-36(38)40)43(51)49-47-24-8-14-31-10-4-2-5-11-31)39-29-46-41-23-21-35(27-37(39)41)44(52)50-48-25-9-15-32-12-6-3-7-13-32/h2-29,42,45-46H,1H3,(H,49,51)(H,50,52)/b14-8+,15-9+,47-24+,48-25+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
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