BDBM50284150 ((2R,5S)-5-Benzyl-1-{(S)-2-[(S)-2-tert-butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-4-methyl-pentanoyl}-3-oxo-piperazin-2-yl)-acetic acid::CHEMBL172135
SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)N1C[C@H](Cc2ccccc2)NC(=O)[C@H]1CC(O)=O
InChI Key: InChIKey=QKEXHCTVRMIPST-HSNHEXMOSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholecystokinin receptor (Mus musculus) | BDBM50284150 (((2R,5S)-5-Benzyl-1-{(S)-2-[(S)-2-tert-butoxycarbo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Concentration producing half-maximal inhibition of specific binding of [125I]- CCK-8 to CCK receptors on mouse pancreatic membranes (CCK-A) | Bioorg Med Chem Lett 4: 867-872 (1994) Article DOI: 10.1016/S0960-894X(01)80253-5 BindingDB Entry DOI: 10.7270/Q2WQ03QK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor (MOUSE) | BDBM50284150 (((2R,5S)-5-Benzyl-1-{(S)-2-[(S)-2-tert-butoxycarbo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Concentration producing half-maximal inhibition of specific binding of [125I]- CCK-8 to CCK receptors mouse forebrain membranes (CCK-B) | Bioorg Med Chem Lett 4: 867-872 (1994) Article DOI: 10.1016/S0960-894X(01)80253-5 BindingDB Entry DOI: 10.7270/Q2WQ03QK | |||||||||||
More data for this Ligand-Target Pair |