BDBM50284205 2,3-Dimethyl-1-(3-phenyl-propyl)-1,7-dihydro-5-oxa-1,7-diaza-indene-4,6-dione::CHEMBL174956

SMILES: Cc1c(C)c2c(O)oc(=O)nc2n1CCCc1ccccc1

InChI Key: InChIKey=KGGJQHJXZKQZIQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284205   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil elastase (Homo sapiens (Human))	BDBM50284205 (2,3-Dimethyl-1-(3-phenyl-propyl)-1,7-dihydro-5-oxa...) Show SMILES Cc1c(C)c2c(O)oc(=O)nc2n1CCCc1ccccc1 Show InChI InChI=1S/C17H18N2O3/c1-11-12(2)19(10-6-9-13-7-4-3-5-8-13)15-14(11)16(20)22-17(21)18-15/h3-5,7-8,20H,6,9-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	8.95E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound against human leukocyte elastase using MeO-Suc-Ala-Ala-Pro-Val-pNA (416 uM) as substrate;No Inhibition				Bioorg Med Chem Lett 4: 949-954 (1994) Article DOI: 10.1016/S0960-894X(01)80270-5 BindingDB Entry DOI: 10.7270/Q27W6C4C
					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bos taurus (bovine))	BDBM50284205 (2,3-Dimethyl-1-(3-phenyl-propyl)-1,7-dihydro-5-oxa...) Show SMILES Cc1c(C)c2c(O)oc(=O)nc2n1CCCc1ccccc1 Show InChI InChI=1S/C17H18N2O3/c1-11-12(2)19(10-6-9-13-7-4-3-5-8-13)15-14(11)16(20)22-17(21)18-15/h3-5,7-8,20H,6,9-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.22E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of porcine chymotrypsin.				Bioorg Med Chem Lett 4: 949-954 (1994) Article DOI: 10.1016/S0960-894X(01)80270-5 BindingDB Entry DOI: 10.7270/Q27W6C4C
					More data for this Ligand-Target Pair