BDBM50284316 12-(3-dimethylamino-2-hydroxypropyl)-9-methoxy-13-methyl-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::CHEMBL345639

SMILES: COc1ccc2n(CC(O)CN(C)C)c3c(c4CNC(=O)c4c4c5ccccc5n(C)c34)c2c1

InChI Key: InChIKey=XIXAQIBBURNBNH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50284316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM50284316 (12-(3-dimethylamino-2-hydroxypropyl)-9-methoxy-13-...) Show SMILES COc1ccc2n(CC(O)CN(C)C)c3c(c4CNC(=O)c4c4c5ccccc5n(C)c34)c2c1 Show InChI InChI=1S/C27H28N4O3/c1-29(2)13-15(32)14-31-21-10-9-16(34-4)11-18(21)22-19-12-28-27(33)24(19)23-17-7-5-6-8-20(17)30(3)25(23)26(22)31/h5-11,15,32H,12-14H2,1-4H3,(H,28,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of Myosin light chain kinase from chicken gizzard				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
cGMP-Dependent Protein Kinase (Bos taurus (bovine))	BDBM50284316 (12-(3-dimethylamino-2-hydroxypropyl)-9-methoxy-13-...) Show SMILES COc1ccc2n(CC(O)CN(C)C)c3c(c4CNC(=O)c4c4c5ccccc5n(C)c34)c2c1 Show InChI InChI=1S/C27H28N4O3/c1-29(2)13-15(32)14-31-21-10-9-16(34-4)11-18(21)22-19-12-28-27(33)24(19)23-17-7-5-6-8-20(17)30(3)25(23)26(22)31/h5-11,15,32H,12-14H2,1-4H3,(H,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of cGMP-dependent protein kinase from bovine lung				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BLK (Mus musculus)	BDBM50284316 (12-(3-dimethylamino-2-hydroxypropyl)-9-methoxy-13-...) Show SMILES COc1ccc2n(CC(O)CN(C)C)c3c(c4CNC(=O)c4c4c5ccccc5n(C)c34)c2c1 Show InChI InChI=1S/C27H28N4O3/c1-29(2)13-15(32)14-31-21-10-9-16(34-4)11-18(21)22-19-12-28-27(33)24(19)23-17-7-5-6-8-20(17)30(3)25(23)26(22)31/h5-11,15,32H,12-14H2,1-4H3,(H,28,33)	MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of general tyrosine-specific protein kinase activity from murine B cell lysate				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair