BDBM50284457 CHEMBL15671::[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenoxy]-phenyl-acetic acid

SMILES: CCc1nc2c(C)cc(C)nc2n1Cc1ccc(OC(C(O)=O)c2ccccc2)cc1

InChI Key: InChIKey=LEBQJIIQZNRPHY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT2 (RAT)	BDBM50284457 (CHEMBL15671 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,5...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(OC(C(O)=O)c2ccccc2)cc1 Show InChI InChI=1S/C25H25N3O3/c1-4-21-27-22-16(2)14-17(3)26-24(22)28(21)15-18-10-12-20(13-11-18)31-23(25(29)30)19-8-6-5-7-9-19/h5-14,23H,4,15H2,1-3H3,(H,29,30)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rat midbrain membrane (AT2 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50284457 (CHEMBL15671 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,5...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(OC(C(O)=O)c2ccccc2)cc1 Show InChI InChI=1S/C25H25N3O3/c1-4-21-27-22-16(2)14-17(3)26-24(22)28(21)15-18-10-12-20(13-11-18)31-23(25(29)30)19-8-6-5-7-9-19/h5-14,23H,4,15H2,1-3H3,(H,29,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair