BDBM50284473 CHEMBL274243::N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetyl}-benzenesulfonamide

SMILES: CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(=O)NS(=O)(=O)c1ccccc1)c1ccc2OCOc2c1

InChI Key: InChIKey=VPQXUAPGMAIEDK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EDNRB (Homo sapiens (Human))	BDBM50284473 (CHEMBL274243 | N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(=O)NS(=O)(=O)c1ccccc1)c1ccc2OCOc2c1 Show InChI InChI=1S/C38H42N4O6S/c1-6-12-27-19-26(22-42-33(8-3)40-34-24(4)18-25(5)39-37(34)42)20-28(13-7-2)35(27)48-36(29-16-17-31-32(21-29)47-23-46-31)38(43)41-49(44,45)30-14-10-9-11-15-30/h9-11,14-21,36H,6-8,12-13,22-23H2,1-5H3,(H,41,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human endothelin B (ETB) receptor expressed in CHO cells				Bioorg Med Chem Lett 5: 1155-1158 (1995) Article DOI: 10.1016/0960-894X(95)00186-W BindingDB Entry DOI: 10.7270/Q2DF6R5F
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50284473 (CHEMBL274243 | N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(=O)NS(=O)(=O)c1ccccc1)c1ccc2OCOc2c1 Show InChI InChI=1S/C38H42N4O6S/c1-6-12-27-19-26(22-42-33(8-3)40-34-24(4)18-25(5)39-37(34)42)20-28(13-7-2)35(27)48-36(29-16-17-31-32(21-29)47-23-46-31)38(43)41-49(44,45)30-14-10-9-11-15-30/h9-11,14-21,36H,6-8,12-13,22-23H2,1-5H3,(H,41,43)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human endothelin A (ETA) receptor expressed in CHO cells				Bioorg Med Chem Lett 5: 1155-1158 (1995) Article DOI: 10.1016/0960-894X(95)00186-W BindingDB Entry DOI: 10.7270/Q2DF6R5F
					More data for this Ligand-Target Pair