BDBM50284685 (3S,4S)-6-(5-Bromo-6-methyl-pyridin-2-ylmethoxy)-3-pyridin-3-ylmethyl-chroman-4-ol::CHEMBL31325
SMILES: Cc1nc(COc2ccc3OC[C@H](Cc4cccnc4)[C@H](O)c3c2)ccc1Br
InChI Key: InChIKey=XPORXQYLGDNCDH-AOMKIAJQSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cysteinyl leukotriene receptor 1 (GUINEA PIG) | BDBM50284685 ((3S,4S)-6-(5-Bromo-6-methyl-pyridin-2-ylmethoxy)-3...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 1.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for the inhibition of [3H]-leukotriene D4 binding to LTD4 receptor in guinea pig lung membranes | Bioorg Med Chem Lett 5: 1371-1376 (1995) Article DOI: 10.1016/0960-894X(95)00226-J BindingDB Entry DOI: 10.7270/Q2QR4X29 | |||||||||||
More data for this Ligand-Target Pair |