BDBM50284708 5-(4-chlorophenyl)-7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL283200

SMILES: OC(=O)[C@@H]1[C@@H]([C@H]2[C@@H]1c1ccccc1C(=O)c1cc(ccc21)-c1ccc(Cl)cc1)C(O)=O

InChI Key: InChIKey=RBIUYHJGRUEIPU-LNRXMEIDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284708   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50284708 (5-(4-chlorophenyl)-7-oxo-(1R,2S)-2,2a,7,11b-tetrah...) Show SMILES OC(=O)[C@@H]1[C@@H]([C@H]2[C@@H]1c1ccccc1C(=O)c1cc(ccc21)-c1ccc(Cl)cc1)C(O)=O Show InChI InChI=1S/C25H17ClO5/c26-14-8-5-12(6-9-14)13-7-10-16-18(11-13)23(27)17-4-2-1-3-15(17)19-20(16)22(25(30)31)21(19)24(28)29/h1-11,19-22H,(H,28,29)(H,30,31)/t19-,20+,21-,22+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards cloned human ETA receptor				Bioorg Med Chem Lett 5: 1401-1404 (1995) Article DOI: 10.1016/0960-894X(95)00230-Q BindingDB Entry DOI: 10.7270/Q2BK1C9J
					More data for this Ligand-Target Pair
EDNRB (Homo sapiens (Human))	BDBM50284708 (5-(4-chlorophenyl)-7-oxo-(1R,2S)-2,2a,7,11b-tetrah...) Show SMILES OC(=O)[C@@H]1[C@@H]([C@H]2[C@@H]1c1ccccc1C(=O)c1cc(ccc21)-c1ccc(Cl)cc1)C(O)=O Show InChI InChI=1S/C25H17ClO5/c26-14-8-5-12(6-9-14)13-7-10-16-18(11-13)23(27)17-4-2-1-3-15(17)19-20(16)22(25(30)31)21(19)24(28)29/h1-11,19-22H,(H,28,29)(H,30,31)/t19-,20+,21-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards cloned human ETB receptor				Bioorg Med Chem Lett 5: 1401-1404 (1995) Article DOI: 10.1016/0960-894X(95)00230-Q BindingDB Entry DOI: 10.7270/Q2BK1C9J
					More data for this Ligand-Target Pair