BDBM50284804 2-((5S,7R)-9-Bromo-7-methyl-2,3-dioxo-2,3,6,7-tetrahydro-1H,5H-pyrido[1,2,3-de]quinoxalin-5-yl)-N-phenyl-acetamide::CHEMBL418055
SMILES: C[C@@H]1C[C@@H](CC(=O)Nc2ccccc2)n2c3c1cc(Br)cc3[nH]c(=O)c2=O
InChI Key: InChIKey=VOURPNBEHYEEGV-RISCZKNCSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50284804 (2-((5S,7R)-9-Bromo-7-methyl-2,3-dioxo-2,3,6,7-tetr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Affinity measured by using [3H]5,7-dichlorokynurenic acid (DCKA) for the glycine binding site of NMDA receptor | Bioorg Med Chem Lett 5: 1527-1532 (1995) Article DOI: 10.1016/0960-894X(95)00243-M BindingDB Entry DOI: 10.7270/Q2K35TKC | |||||||||||
More data for this Ligand-Target Pair |