BDBM50284895 (1-{(R)-1-{3-[(E)-2-(4-Cyclopentyl-thiazol-2-yl)-vinyl]-phenyl}-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid::CHEMBL43602

SMILES: CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2nc(cs2)C2CCCC2)c1

InChI Key: InChIKey=NQZKBKBKFQKUAI-QZOFMVIASA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284895   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50284895 ((1-{(R)-1-{3-[(E)-2-(4-Cyclopentyl-thiazol-2-yl)-v...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2nc(cs2)C2CCCC2)c1 Show InChI InChI=1S/C34H41NO3S2/c1-33(2,38)28-13-6-5-9-25(28)15-16-30(40-23-34(18-19-34)21-32(36)37)27-12-7-8-24(20-27)14-17-31-35-29(22-39-31)26-10-3-4-11-26/h5-9,12-14,17,20,22,26,30,38H,3-4,10-11,15-16,18-19,21,23H2,1-2H3,(H,36,37)/b17-14+/t30-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-LTD4 binding on guinea-pig lung membranes				Bioorg Med Chem Lett 5: 1615-1620 (1995) Article DOI: 10.1016/0960-894X(95)00265-U BindingDB Entry DOI: 10.7270/Q2NV9J6V
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50284895 ((1-{(R)-1-{3-[(E)-2-(4-Cyclopentyl-thiazol-2-yl)-v...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2nc(cs2)C2CCCC2)c1 Show InChI InChI=1S/C34H41NO3S2/c1-33(2,38)28-13-6-5-9-25(28)15-16-30(40-23-34(18-19-34)21-32(36)37)27-12-7-8-24(20-27)14-17-31-35-29(22-39-31)26-10-3-4-11-26/h5-9,12-14,17,20,22,26,30,38H,3-4,10-11,15-16,18-19,21,23H2,1-2H3,(H,36,37)/b17-14+/t30-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]LTD4 binding on guinea-pig lung membranes				Bioorg Med Chem Lett 5: 1615-1620 (1995) Article DOI: 10.1016/0960-894X(95)00265-U BindingDB Entry DOI: 10.7270/Q2NV9J6V
					More data for this Ligand-Target Pair