BDBM50285334 (S)-3-Biphenyl-4-yl-2-(phosphonomethyl-amino)-propionic acid::CHEMBL273216

SMILES: OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NCP(O)(O)=O

InChI Key: InChIKey=FHHVMVKHXJMNJE-HNNXBMFYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM50285334 ((S)-3-Biphenyl-4-yl-2-(phosphonomethyl-amino)-prop...) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NCP(O)(O)=O Show InChI InChI=1S/C16H18NO5P/c18-16(19)15(17-11-23(20,21)22)10-12-6-8-14(9-7-12)13-4-2-1-3-5-13/h1-9,15,17H,10-11H2,(H,18,19)(H2,20,21,22)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against neutral endopeptidase at 30 mg/kg dose				Bioorg Med Chem Lett 5: 151-154 (1995) Article DOI: 10.1016/0960-894X(94)00475-U BindingDB Entry DOI: 10.7270/Q2B85831
					More data for this Ligand-Target Pair
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50285334 ((S)-3-Biphenyl-4-yl-2-(phosphonomethyl-amino)-prop...) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NCP(O)(O)=O Show InChI InChI=1S/C16H18NO5P/c18-16(19)15(17-11-23(20,21)22)10-12-6-8-14(9-7-12)13-4-2-1-3-5-13/h1-9,15,17H,10-11H2,(H,18,19)(H2,20,21,22)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against neutral endopeptidase (NEP)				Bioorg Med Chem Lett 5: 145-150 (1995) Article DOI: 10.1016/0960-894X(94)00474-T BindingDB Entry DOI: 10.7270/Q2G160SW
					More data for this Ligand-Target Pair