BDBM50285360 5-Ethyl-10-methyl-5,10-dihydro-3,5,6,10-tetraaza-dibenzo[a,d]cyclohepten-11-one::CHEMBL46562

SMILES: CCN1c2cnccc2C(=O)N(C)c2cccnc12

InChI Key: InChIKey=RANNWRQNOQFPNO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285360   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50285360 (5-Ethyl-10-methyl-5,10-dihydro-3,5,6,10-tetraaza-d...) Show SMILES CCN1c2cnccc2C(=O)N(C)c2cccnc12 Show InChI InChI=1S/C14H14N4O/c1-3-18-12-9-15-8-6-10(12)14(19)17(2)11-5-4-7-16-13(11)18/h4-9H,3H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Reverse transcriptase(RT) was determined				Bioorg Med Chem Lett 5: 163-166 (1995) Article DOI: 10.1016/0960-894X(94)00478-X BindingDB Entry DOI: 10.7270/Q22R3RM4
					More data for this Ligand-Target Pair