BDBM50285447 CHEMBL53397::{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-ylsulfanyl]-pentyl}-butyl-(5-tert-butyl-benzooxazol-2-yl)-amine

SMILES: CCCCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)c1nc2cc(ccc2o1)C(C)(C)C

InChI Key: InChIKey=ROYQJKVQYGXCIA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl coenzyme A:cholesterol acyltransferase 1 (Mus musculus)	BDBM50285447 (CHEMBL53397 | {5-[4,5-Bis-(4-methoxy-phenyl)-1H-im...) Show SMILES CCCCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)c1nc2cc(ccc2o1)C(C)(C)C Show InChI InChI=1S/C37H46N4O3S/c1-7-8-22-41(36-38-31-25-28(37(2,3)4)16-21-32(31)44-36)23-10-9-11-24-45-35-39-33(26-12-17-29(42-5)18-13-26)34(40-35)27-14-19-30(43-6)20-15-27/h12-21,25H,7-11,22-24H2,1-6H3,(H,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture				Bioorg Med Chem Lett 5: 177-180 (1995) Article DOI: 10.1016/0960-894X(95)00003-C BindingDB Entry DOI: 10.7270/Q2PG1RQJ
					More data for this Ligand-Target Pair
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50285447 (CHEMBL53397 | {5-[4,5-Bis-(4-methoxy-phenyl)-1H-im...) Show SMILES CCCCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)c1nc2cc(ccc2o1)C(C)(C)C Show InChI InChI=1S/C37H46N4O3S/c1-7-8-22-41(36-38-31-25-28(37(2,3)4)16-21-32(31)44-36)23-10-9-11-24-45-35-39-33(26-12-17-29(42-5)18-13-26)34(40-35)27-14-19-30(43-6)20-15-27/h12-21,25H,7-11,22-24H2,1-6H3,(H,39,40)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes was measured by using AIV assay				Bioorg Med Chem Lett 5: 177-180 (1995) Article DOI: 10.1016/0960-894X(95)00003-C BindingDB Entry DOI: 10.7270/Q2PG1RQJ
					More data for this Ligand-Target Pair