BDBM50285632 (S)-2-[((R)-2-Benzyl-3-hydroxycarbamoyl-propionyl)-methyl-amino]-propionic acid::CHEMBL86211
SMILES: C[C@H](N(C)C(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C(O)=O
InChI Key: InChIKey=YHRYSPKQPIQJCW-CMPLNLGQSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angiotensin-converting enzyme (Oryctolagus cuniculus) | BDBM50285632 ((S)-2-[((R)-2-Benzyl-3-hydroxycarbamoyl-propionyl)...) | MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit lung angiotensin-converting enzyme(ACE) | Bioorg Med Chem Lett 5: 2517-2522 (1995) Article DOI: 10.1016/0960-894X(95)00441-U BindingDB Entry DOI: 10.7270/Q2959J1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A4 hydrolase (Homo sapiens (Human)) | BDBM50285632 ((S)-2-[((R)-2-Benzyl-3-hydroxycarbamoyl-propionyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human Leukotriene A4 hydrolase | Bioorg Med Chem Lett 5: 2517-2522 (1995) Article DOI: 10.1016/0960-894X(95)00441-U BindingDB Entry DOI: 10.7270/Q2959J1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Oryctolagus cuniculus (rabbit)) | BDBM50285632 ((S)-2-[((R)-2-Benzyl-3-hydroxycarbamoyl-propionyl)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rabbit kidney neutral endopeptidase (NEP) | Bioorg Med Chem Lett 5: 2517-2522 (1995) Article DOI: 10.1016/0960-894X(95)00441-U BindingDB Entry DOI: 10.7270/Q2959J1M | |||||||||||
More data for this Ligand-Target Pair |