BDBM50285680 (1-{(R)-1-[3-(2,3-Dichloro-thieno[3,2-b]pyridin-5-ylmethoxy)-phenyl]-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid::CHEMBL85633

SMILES: CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(OCc2ccc3sc(Cl)c(Cl)c3n2)c1

InChI Key: InChIKey=KBBBPRAKKDDMRH-RUZDIDTESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50285680 ((1-{(R)-1-[3-(2,3-Dichloro-thieno[3,2-b]pyridin-5-...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(OCc2ccc3sc(Cl)c(Cl)c3n2)c1 Show InChI InChI=1S/C32H33Cl2NO4S2/c1-31(2,38)24-9-4-3-6-20(24)10-12-25(40-19-32(14-15-32)17-27(36)37)21-7-5-8-23(16-21)39-18-22-11-13-26-29(35-22)28(33)30(34)41-26/h3-9,11,13,16,25,38H,10,12,14-15,17-19H2,1-2H3,(H,36,37)/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	2.01	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes				Bioorg Med Chem Lett 5: 2551-2556 (1995) Article DOI: 10.1016/0960-894X(95)00448-3 BindingDB Entry DOI: 10.7270/Q2W37W8Q
					More data for this Ligand-Target Pair