BDBM50285701 Anthranilamide derivative::CHEMBL313767
SMILES: O[C@@H](C[C@H](Cc1ccccc1)NC(=O)c1ccccc1NC(=O)OCc1ccccn1)[C@H](Cc1ccccc1)NC(=O)c1ccccc1NC(=O)OCc1ccccn1
InChI Key: InChIKey=PKBPUJCUWPCIQB-XGXWMDOZSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Human immunodeficiency virus type 1 protease (Human immunodeficiency virus type 1) | BDBM50285701 (Anthranilamide derivative | CHEMBL313767) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of HIV protease using fluorogenic substrate | Bioorg Med Chem Lett 5: 2557-2562 (1995) Article DOI: 10.1016/0960-894X(95)00449-4 BindingDB Entry DOI: 10.7270/Q2RB74KT | |||||||||||
More data for this Ligand-Target Pair |