Found 6 hits for monomerid = 50285918 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Retinoic acid receptor gamma
(Homo sapiens (Human)) | BDBM50285918
(5-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)Show SMILES C\C(=C/c1ccc(s1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C22H26O2S/c1-14(12-16-7-9-19(25-16)20(23)24)15-6-8-17-18(13-15)22(4,5)11-10-21(17,2)3/h6-9,12-13H,10-11H2,1-5H3,(H,23,24)/b14-12+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Agonist activity for retinoic acid receptor RAR gamma in transcriptional activation assay |
Bioorg Med Chem Lett 5: 2729-2734 (1995)
Article DOI: 10.1016/0960-894X(95)00455-3 BindingDB Entry DOI: 10.7270/Q22N527N |
More data for this Ligand-Target Pair | |
Retinoic acid receptor alpha
(Homo sapiens (Human)) | BDBM50285918
(5-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)Show SMILES C\C(=C/c1ccc(s1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C22H26O2S/c1-14(12-16-7-9-19(25-16)20(23)24)15-6-8-17-18(13-15)22(4,5)11-10-21(17,2)3/h6-9,12-13H,10-11H2,1-5H3,(H,23,24)/b14-12+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | n/a | n/a | 690 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Agonist activity for retinoic acid receptor RAR alpha in transcriptional activation assay |
Bioorg Med Chem Lett 5: 2729-2734 (1995)
Article DOI: 10.1016/0960-894X(95)00455-3 BindingDB Entry DOI: 10.7270/Q22N527N |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50285918
(5-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)Show SMILES C\C(=C/c1ccc(s1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C22H26O2S/c1-14(12-16-7-9-19(25-16)20(23)24)15-6-8-17-18(13-15)22(4,5)11-10-21(17,2)3/h6-9,12-13H,10-11H2,1-5H3,(H,23,24)/b14-12+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Agonist activity for retinoic acid receptor RXR beta in transcriptional activation assay |
Bioorg Med Chem Lett 5: 2729-2734 (1995)
Article DOI: 10.1016/0960-894X(95)00455-3 BindingDB Entry DOI: 10.7270/Q22N527N |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50285918
(5-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)Show SMILES C\C(=C/c1ccc(s1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C22H26O2S/c1-14(12-16-7-9-19(25-16)20(23)24)15-6-8-17-18(13-15)22(4,5)11-10-21(17,2)3/h6-9,12-13H,10-11H2,1-5H3,(H,23,24)/b14-12+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Agonist activity for retinoic acid receptor RXR gamma in transcriptional activation assay |
Bioorg Med Chem Lett 5: 2729-2734 (1995)
Article DOI: 10.1016/0960-894X(95)00455-3 BindingDB Entry DOI: 10.7270/Q22N527N |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50285918
(5-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)Show SMILES C\C(=C/c1ccc(s1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C22H26O2S/c1-14(12-16-7-9-19(25-16)20(23)24)15-6-8-17-18(13-15)22(4,5)11-10-21(17,2)3/h6-9,12-13H,10-11H2,1-5H3,(H,23,24)/b14-12+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Agonist activity for retinoic acid receptor RXR alpha in transcriptional activation assay |
Bioorg Med Chem Lett 5: 2729-2734 (1995)
Article DOI: 10.1016/0960-894X(95)00455-3 BindingDB Entry DOI: 10.7270/Q22N527N |
More data for this Ligand-Target Pair | |
Retinoic acid receptor beta
(Homo sapiens (Human)) | BDBM50285918
(5-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)Show SMILES C\C(=C/c1ccc(s1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C22H26O2S/c1-14(12-16-7-9-19(25-16)20(23)24)15-6-8-17-18(13-15)22(4,5)11-10-21(17,2)3/h6-9,12-13H,10-11H2,1-5H3,(H,23,24)/b14-12+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | n/a | n/a | 29 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Agonist activity for retinoic acid receptor RAR beta in transcriptional activation assay |
Bioorg Med Chem Lett 5: 2729-2734 (1995)
Article DOI: 10.1016/0960-894X(95)00455-3 BindingDB Entry DOI: 10.7270/Q22N527N |
More data for this Ligand-Target Pair | |