BDBM50285943 (4-Chloro-phenyl)-(2-morpholin-4-yl-8-propyl-9H-purin-6-yl)-amine::CHEMBL318254

SMILES: CCCc1nc2nc(nc(Nc3ccc(Cl)cc3)c2[nH]1)N1CCOCC1

InChI Key: InChIKey=BHCLMCDCKVEHIB-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TACR2 (HAMSTER)	BDBM50285943 ((4-Chloro-phenyl)-(2-morpholin-4-yl-8-propyl-9H-pu...) Show SMILES CCCc1nc2nc(nc(Nc3ccc(Cl)cc3)c2[nH]1)N1CCOCC1 Show InChI InChI=1S/C18H21ClN6O/c1-2-3-14-21-15-16(20-13-6-4-12(19)5-7-13)23-18(24-17(15)22-14)25-8-10-26-11-9-25/h4-7H,2-3,8-11H2,1H3,(H2,20,21,22,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-NKA from Tachykinin receptor 2 found in hamster urinary bladder membrane (HUBM)				Bioorg Med Chem Lett 5: 2879-2884 (1995) Article DOI: 10.1016/0960-894X(95)00502-K BindingDB Entry DOI: 10.7270/Q2DV1JTQ
					More data for this Ligand-Target Pair
Neurokinin 2 receptor (Homo sapiens (Human))	BDBM50285943 ((4-Chloro-phenyl)-(2-morpholin-4-yl-8-propyl-9H-pu...) Show SMILES CCCc1nc2nc(nc(Nc3ccc(Cl)cc3)c2[nH]1)N1CCOCC1 Show InChI InChI=1S/C18H21ClN6O/c1-2-3-14-21-15-16(20-13-6-4-12(19)5-7-13)23-18(24-17(15)22-14)25-8-10-26-11-9-25/h4-7H,2-3,8-11H2,1H3,(H2,20,21,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2.34E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-NKA from the cloned human NK2 receptor				Bioorg Med Chem Lett 5: 2879-2884 (1995) Article DOI: 10.1016/0960-894X(95)00502-K BindingDB Entry DOI: 10.7270/Q2DV1JTQ
					More data for this Ligand-Target Pair