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BDBM50286018 6-(4-Hydroxymethyl-phenyl)-3-((R)-3-pyridin-3-yl-1H-pyrrolo[1,2-c]thiazole-7-carbonyl)-indole-1-carboxylic acid dimethylamide::CHEMBL99070

SMILES: CN(C)C(=O)n1cc(C(=O)c2ccn3[C@H](SCc23)c2cccnc2)c2ccc(cc12)-c1ccc(CO)cc1

InChI Key: InChIKey=YGVHBGFLTNPNGY-GDLZYMKVSA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286018   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Cavia porcellus)		BDBM50286018
PNG
(6-(4-Hydroxymethyl-phenyl)-3-((R)-3-pyridin-3-yl-1...)
Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccn3[C@H](SCc23)c2cccnc2)c2ccc(cc12)-c1ccc(CO)cc1
Show InChI InChI=1S/C30H26N4O3S/c1-32(2)30(37)34-16-25(23-10-9-21(14-26(23)34)20-7-5-19(17-35)6-8-20)28(36)24-11-13-33-27(24)18-38-29(33)22-4-3-12-31-15-22/h3-16,29,35H,17-18H2,1-2H3/t29-/m1/s1
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Similars
Article
 16n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity for platelet activating factor receptor using [3H]-PAF in rabbit platelet membranes

Bioorg Med Chem Lett 5: 2913-2918 (1995)


Article DOI: 10.1016/0960-894X(95)00511-Q
BindingDB Entry DOI: 10.7270/Q2NC6157
More data for this
Ligand-Target Pair