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BDBM50286020 3-[[(Z)-3-Dimethylamino-propoxyimino]-((R)-3-pyridin-3-yl-1H-pyrrolo[1,2-c]thiazol-7-yl)-methyl]-6-(4-fluoro-phenyl)-indole-1-carboxylic acid dimethylamide::CHEMBL316911

SMILES: CN(C)CCCO\N=C(/c1ccn2[C@H](SCc12)c1cccnc1)c1cn(C(=O)N(C)C)c2cc(ccc12)-c1ccc(F)cc1

InChI Key: InChIKey=JVYJXVDUHSUUOO-ZOLYHGSPSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286020   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Cavia porcellus)		BDBM50286020
PNG
(3-[[(Z)-3-Dimethylamino-propoxyimino]-((R)-3-pyrid...)
Show SMILES CN(C)CCCO\N=C(/c1ccn2[C@H](SCc12)c1cccnc1)c1cn(C(=O)N(C)C)c2cc(ccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C34H35FN6O2S/c1-38(2)16-6-18-43-37-32(28-14-17-40-31(28)22-44-33(40)25-7-5-15-36-20-25)29-21-41(34(42)39(3)4)30-19-24(10-13-27(29)30)23-8-11-26(35)12-9-23/h5,7-15,17,19-21,33H,6,16,18,22H2,1-4H3/b37-32+/t33-/m1/s1
MMDB

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Similars
Article
 160n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity for platelet activating factor receptor using [3H]-PAF in rabbit platelet membranes

Bioorg Med Chem Lett 5: 2913-2918 (1995)


Article DOI: 10.1016/0960-894X(95)00511-Q
BindingDB Entry DOI: 10.7270/Q2NC6157
More data for this
Ligand-Target Pair