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BDBM50286029 CHEMBL317335::indole analogue

SMILES: CN(C)C(=O)n1cc(\C(=N\OC(=O)c2ccccc2S(O)(=O)=O)c2ccn3[C@H](SCc23)c2cccnc2)c2ccc(cc12)-c1ccc(F)cc1

InChI Key: InChIKey=DJPQYNAGDJQHLP-GLXKZASXSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286029   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Cavia porcellus)		BDBM50286029
PNG
(CHEMBL317335 | indole analogue)
Show SMILES CN(C)C(=O)n1cc(\C(=N\OC(=O)c2ccccc2S(O)(=O)=O)c2ccn3[C@H](SCc23)c2cccnc2)c2ccc(cc12)-c1ccc(F)cc1
Show InChI InChI=1S/C36H28FN5O6S2/c1-40(2)36(44)42-20-29(26-14-11-23(18-30(26)42)22-9-12-25(37)13-10-22)33(39-48-35(43)28-7-3-4-8-32(28)50(45,46)47)27-15-17-41-31(27)21-49-34(41)24-6-5-16-38-19-24/h3-20,34H,21H2,1-2H3,(H,45,46,47)/b39-33+/t34-/m1/s1
MMDB

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Article
 11n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity for platelet activating factor receptor using [3H]-PAF in rabbit platelet membranes

Bioorg Med Chem Lett 5: 2913-2918 (1995)


Article DOI: 10.1016/0960-894X(95)00511-Q
BindingDB Entry DOI: 10.7270/Q2NC6157
More data for this
Ligand-Target Pair