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BDBM50286036 3-[[(Z)-2-Dimethylamino-ethoxyimino]-((R)-3-pyridin-3-yl-1H-pyrrolo[1,2-c]thiazol-7-yl)-methyl]-6-(4-fluoro-phenyl)-indole-1-carboxylic acid dimethylamide::CHEMBL329498

SMILES: CN(C)CCO\N=C(/c1ccn2[C@H](SCc12)c1cccnc1)c1cn(C(=O)N(C)C)c2cc(ccc12)-c1ccc(F)cc1

InChI Key: InChIKey=IKUVLHPTCPSEIE-ZWWQSBRASA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286036   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)		BDBM50286036
PNG
(3-[[(Z)-2-Dimethylamino-ethoxyimino]-((R)-3-pyridi...)
Show SMILES CN(C)CCO\N=C(/c1ccn2[C@H](SCc12)c1cccnc1)c1cn(C(=O)N(C)C)c2cc(ccc12)-c1ccc(F)cc1
Show InChI InChI=1S/C33H33FN6O2S/c1-37(2)16-17-42-36-31(27-13-15-39-30(27)21-43-32(39)24-6-5-14-35-19-24)28-20-40(33(41)38(3)4)29-18-23(9-12-26(28)29)22-7-10-25(34)11-8-22/h5-15,18-20,32H,16-17,21H2,1-4H3/b36-31+/t32-/m1/s1
MMDB

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Article
 200n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity for platelet activating factor receptor using [3H]-PAF in rabbit platelet membranes

Bioorg Med Chem Lett 5: 2913-2918 (1995)


Article DOI: 10.1016/0960-894X(95)00511-Q
BindingDB Entry DOI: 10.7270/Q2NC6157
More data for this
Ligand-Target Pair