BDBM50286044 CHEMBL320371::[6-(4-Fluoro-phenyl)-3-((R)-3-pyridin-3-yl-1H-pyrrolo[1,2-c]thiazole-7-carbonyl)-indol-1-yl]-(4-methyl-piperazin-1-yl)-methanone

SMILES: CN1CCN(CC1)C(=O)n1cc(C(=O)c2ccn3[C@H](SCc23)c2cccnc2)c2ccc(cc12)-c1ccc(F)cc1

InChI Key: InChIKey=QHUHHKMQSQGZPW-WJOKGBTCSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286044   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Cavia porcellus)	BDBM50286044 (CHEMBL320371 | [6-(4-Fluoro-phenyl)-3-((R)-3-pyrid...) Show SMILES CN1CCN(CC1)C(=O)n1cc(C(=O)c2ccn3[C@H](SCc23)c2cccnc2)c2ccc(cc12)-c1ccc(F)cc1 Show InChI InChI=1S/C32H28FN5O2S/c1-35-13-15-36(16-14-35)32(40)38-19-27(25-9-6-22(17-28(25)38)21-4-7-24(33)8-5-21)30(39)26-10-12-37-29(26)20-41-31(37)23-3-2-11-34-18-23/h2-12,17-19,31H,13-16,20H2,1H3/t31-/m1/s1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for platelet activating factor receptor using [3H]-PAF in rabbit platelet membranes				Bioorg Med Chem Lett 5: 2913-2918 (1995) Article DOI: 10.1016/0960-894X(95)00511-Q BindingDB Entry DOI: 10.7270/Q2NC6157
					More data for this Ligand-Target Pair