BDBM50286116 1-[1-Methyl-5-(4-methyl-piperazin-1-yl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-3-m-tolyl-urea::CHEMBL103229

SMILES: CN1CCN(CC1)C1=NC(NC(=O)Nc2cccc(C)c2)C(=O)N(C)c2ccccc12

InChI Key: InChIKey=KKTVXTKJKYRMBP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (RAT)	BDBM50286116 (1-[1-Methyl-5-(4-methyl-piperazin-1-yl)-2-oxo-2,3-...) Show SMILES CN1CCN(CC1)C1=NC(NC(=O)Nc2cccc(C)c2)C(=O)N(C)c2ccccc12 |t:8| Show InChI InChI=1S/C23H28N6O2/c1-16-7-6-8-17(15-16)24-23(31)26-20-22(30)28(3)19-10-5-4-9-18(19)21(25-20)29-13-11-27(2)12-14-29/h4-10,15,20H,11-14H2,1-3H3,(H2,24,26,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [125I]-BH CCK-8S from Cholecystokinin type A receptor in rat pancreas				Bioorg Med Chem Lett 5: 3023-3026 (1995) Article DOI: 10.1016/0960-894X(95)00530-0 BindingDB Entry DOI: 10.7270/Q2VX0GGR
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50286116 (1-[1-Methyl-5-(4-methyl-piperazin-1-yl)-2-oxo-2,3-...) Show SMILES CN1CCN(CC1)C1=NC(NC(=O)Nc2cccc(C)c2)C(=O)N(C)c2ccccc12 |t:8| Show InChI InChI=1S/C23H28N6O2/c1-16-7-6-8-17(15-16)24-23(31)26-20-22(30)28(3)19-10-5-4-9-18(19)21(25-20)29-13-11-27(2)12-14-29/h4-10,15,20H,11-14H2,1-3H3,(H2,24,26,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [125I]-BH CCK-8S from Cholecystokinin type B receptor in guinea pig cortex				Bioorg Med Chem Lett 5: 3023-3026 (1995) Article DOI: 10.1016/0960-894X(95)00530-0 BindingDB Entry DOI: 10.7270/Q2VX0GGR
					More data for this Ligand-Target Pair